Sandra Sellers Selected Research

edotecarin (J 107088)

8/2010

A phase I dose-escalation study of edotecarin (J-107088) combined with infusional 5-fluorouracil and leucovorin in patients with advanced/metastatic solid tumors.

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Sandra Sellers Research Topics

Disease

3	Neoplasms (Cancer) 08/2010 - 12/2005
2	Hemorrhage 11/2007 - 01/2006
1	Neutropenia 08/2010
1	Diarrhea 11/2007
1	Thrombocytopenia (Thrombopenia) 09/2007
1	Dihydropyrimidine Dehydrogenase Deficiency 09/2007
1	Adenocarcinoma 09/2007
1	Breast Neoplasms (Breast Cancer) 01/2006
1	Duodenitis 01/2006
1	Gastritis 01/2006
1	Hypotension (Low Blood Pressure) 01/2006
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2006
1	Prostatic Neoplasms (Prostate Cancer) 12/2005

Drug/Important Bio-Agent (IBA)

2	Fluorouracil (Carac)FDA LinkGeneric 08/2010 - 09/2007
2	Gemcitabine FDA Link 11/2007 - 01/2006
1	edotecarin (J 107088)IBA 08/2010
1	Leucovorin (Folinic Acid)FDA Link 08/2010
1	Irinotecan (Camptosar)FDA LinkGeneric 11/2007
1	Proton Pump InhibitorsIBA 01/2006
1	Capecitabine (Xeloda)FDA Link 01/2006
1	Pharmaceutical PreparationsIBA 01/2006
1	Heme (Haem)IBA 01/2006
1	GonadotropinsIBA 12/2005
1	AndrogensIBA 12/2005
1	Docetaxel (Taxotere)FDA Link 12/2005
1	Dexamethasone (Maxidex)FDA LinkGeneric 12/2005
1	VaccinesIBA 12/2005
1	Hormones (Hormone)IBA 12/2005
1	Diphtheria-Tetanus VaccineIBA 12/2005
1	Gonadotropin-Releasing Hormone (GnRH)FDA Link 12/2005

Therapy/Procedure

1	Radiotherapy 01/2006
1	Drug Therapy (Chemotherapy) 12/2005